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XOR inhibition with febuxostat accelerates pulmonary endothelial barrier recovery and improves survival in lipopolysaccharide-induced murine sepsis.
Damarla, Mahendra; Johnston, Laura F; Liu, Gigi; Gao, Li; Wang, Lan; Varela, Lidenys; Kolb, Todd M; Kim, Bo S; Damico, Rachel L; Hassoun, Paul M.
Affiliation
  • Damarla M; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland mdamarl1@jhmi.edu.
  • Johnston LF; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Liu G; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Gao L; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Wang L; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Varela L; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Kolb TM; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Kim BS; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Damico RL; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Hassoun PM; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Physiol Rep ; 5(15)2017 Aug.
Article in En | MEDLINE | ID: mdl-28801519
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Xanthine Dehydrogenase / Sepsis / Lung Injury / Febuxostat Limits: Animals Language: En Journal: Physiol Rep Year: 2017 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Xanthine Dehydrogenase / Sepsis / Lung Injury / Febuxostat Limits: Animals Language: En Journal: Physiol Rep Year: 2017 Type: Article