Role for FimH in Extraintestinal Pathogenic Escherichia coli Invasion and Translocation through the Intestinal Epithelium.

Poole, Nina M; Green, Sabrina I; Rajan, Anubama; Vela, Luz E; Zeng, Xi-Lei; Estes, Mary K; Maresso, Anthony W

Poole, Nina M; Green, Sabrina I; Rajan, Anubama; Vela, Luz E; Zeng, Xi-Lei; Estes, Mary K; Maresso, Anthony W.

Affiliation

Poole NM; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Green SI; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Rajan A; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Vela LE; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Zeng XL; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Estes MK; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Maresso AW; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA maresso@bcm.edu.

Infect Immun ; 85(11)2017 11.

Article in En | MEDLINE | ID: mdl-28808163

Subject(s)

Adhesins, Escherichia coli/genetics; Bacterial Translocation/genetics; Epithelial Cells/microbiology; Escherichia coli Infections/microbiology; Extraintestinal Pathogenic Escherichia coli/pathogenicity; Fimbriae Proteins/genetics; Fimbriae, Bacterial/physiology; Animals; Caco-2 Cells; Epithelial Cells/pathology; Escherichia coli Infections/pathology; Extraintestinal Pathogenic Escherichia coli/physiology; Female; Fimbriae Proteins/deficiency; Gene Expression; Humans; Jejunum/microbiology; Jejunum/pathology; Kidney/microbiology; Kidney/pathology; Lung/microbiology; Lung/pathology; Male; Mice, Inbred BALB C; Primary Cell Culture; Spheroids, Cellular/microbiology; Spheroids, Cellular/pathology; Spleen/microbiology; Spleen/pathology; Virulence

Key words

ExPEC; FimH; intestinal epithelium; invasion; translocation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fimbriae, Bacterial / Adhesins, Escherichia coli / Bacterial Translocation / Fimbriae Proteins / Epithelial Cells / Escherichia coli Infections / Extraintestinal Pathogenic Escherichia coli Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Infect Immun Year: 2017 Type: Article Affiliation country: United States

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