Their loss is our gain: regressive evolution in vertebrates provides genomic models for uncovering human disease loci.

Emerling, Christopher A; Widjaja, Andrew D; Nguyen, Nancy N; Springer, Mark S

Emerling, Christopher A; Widjaja, Andrew D; Nguyen, Nancy N; Springer, Mark S.

Affiliation

Emerling CA; Museum of Vertebrate Zoology, University of California, Berkeley, California, USA.
Widjaja AD; Department of Biology, University of California, Riverside, California, USA.
Nguyen NN; Department of Biochemistry, University of California, Riverside, California, USA.
Springer MS; Department of Nutritional Sciences and Toxicology, University of California, Berkeley, California, USA.

J Med Genet ; 54(12): 787-794, 2017 12.

Article in En | MEDLINE | ID: mdl-28814606

Subject(s)

Evolution, Molecular; Genetic Loci; Genetic Predisposition to Disease; Genome; Genomics; Models, Genetic; Vertebrates/genetics; Amelogenesis Imperfecta/diagnosis; Amelogenesis Imperfecta/genetics; Animals; Color Vision Defects/diagnosis; Color Vision Defects/genetics; Genetic Association Studies; Genomics/methods; Humans; Mutation; Phenotype; Pseudogenes

Key words

amelogenesis imperfecta; phylomedicine; pseudogenes; regressive evolution; rod monochromacy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vertebrates / Genome / Evolution, Molecular / Genetic Predisposition to Disease / Genomics / Genetic Loci / Models, Genetic Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: J Med Genet Year: 2017 Type: Article Affiliation country: United States

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