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AMPK downregulates ALK2 via increasing the interaction between Smurf1 and Smad6, leading to inhibition of osteogenic differentiation.
Lin, Hui; Ying, Ying; Wang, Yuan-Yuan; Wang, Gang; Jiang, Shan-Shan; Huang, Deqinag; Luo, Lingyu; Chen, Ye-Guang; Gerstenfeld, Louis C; Luo, Zhijun.
Affiliation
  • Lin H; Jiangxi Province Key Laboratory of Tumor Pathogenesis and Molecular Pathology, Department of Pathophysiology, Schools of Basic Sciences and Pharmaceutical Sciences, Nanchang University Medical College, Nanchang, China; Department of Biochemistry, Boston University School of Medicine, Boston, MA 0211
  • Ying Y; Jiangxi Province Key Laboratory of Tumor Pathogenesis and Molecular Pathology, Department of Pathophysiology, Schools of Basic Sciences and Pharmaceutical Sciences, Nanchang University Medical College, Nanchang, China; Department of Biochemistry, Boston University School of Medicine, Boston, MA 0211
  • Wang YY; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, United States.
  • Wang G; Department of Cardiology, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, United States.
  • Jiang SS; Jiangxi Province Key Laboratory of Tumor Pathogenesis and Molecular Pathology, Department of Pathophysiology, Schools of Basic Sciences and Pharmaceutical Sciences, Nanchang University Medical College, Nanchang, China; Department of Biochemistry, Boston University School of Medicine, Boston, MA 0211
  • Huang D; The Institute of Digestive Diseases, The First Affiliated Hospital, Nanchang University, Nanchang, China.
  • Luo L; The Institute of Digestive Diseases, The First Affiliated Hospital, Nanchang University, Nanchang, China.
  • Chen YG; School of Life Sciences, Tsinghua University, Beijing, China.
  • Gerstenfeld LC; Department of Orthopaedic Surgery, Boston University School of Medicine, Boston, MA, United States.
  • Luo Z; Jiangxi Province Key Laboratory of Tumor Pathogenesis and Molecular Pathology, Department of Pathophysiology, Schools of Basic Sciences and Pharmaceutical Sciences, Nanchang University Medical College, Nanchang, China; Department of Biochemistry, Boston University School of Medicine, Boston, MA 0211
Biochim Biophys Acta Mol Cell Res ; 1864(12): 2369-2377, 2017 Dec.
Article in En | MEDLINE | ID: mdl-28847510

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinases / Activin Receptors, Type I / Ubiquitin-Protein Ligases / Smad6 Protein / Myositis Ossificans Limits: Humans Language: En Journal: Biochim Biophys Acta Mol Cell Res Year: 2017 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinases / Activin Receptors, Type I / Ubiquitin-Protein Ligases / Smad6 Protein / Myositis Ossificans Limits: Humans Language: En Journal: Biochim Biophys Acta Mol Cell Res Year: 2017 Type: Article