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Expression of matrix metalloproteinase 12 is highly specific for non-proliferating invasive trophoblasts in the first trimester and temporally regulated by oxygen-dependent mechanisms including HIF-1A.
Hiden, Ursula; Eyth, Christian P; Majali-Martinez, Alejandro; Desoye, Gernot; Tam-Amersdorfer, Carmen; Huppertz, Berthold; Ghaffari Tabrizi-Wizsy, Nassim.
Affiliation
  • Hiden U; Department of Obstetrics and Gynecology, Medical University of Graz, Graz, Austria. ursula.hiden@medunigraz.at.
  • Eyth CP; Institute of Pathophysiology and Immunology, Center of Molecular Medicine, Medical University of Graz, Graz, Austria.
  • Majali-Martinez A; Department of Obstetrics and Gynecology, Medical University of Graz, Graz, Austria.
  • Desoye G; Department of Obstetrics and Gynecology, Medical University of Graz, Graz, Austria.
  • Tam-Amersdorfer C; Institute of Pathophysiology and Immunology, Center of Molecular Medicine, Medical University of Graz, Graz, Austria.
  • Huppertz B; Institute of Cell Biology, Histology and Embryology, Medical University of Graz, Graz, Austria.
  • Ghaffari Tabrizi-Wizsy N; Institute of Pathophysiology and Immunology, Center of Molecular Medicine, Medical University of Graz, Graz, Austria.
Histochem Cell Biol ; 149(1): 31-42, 2018 Jan.
Article in En | MEDLINE | ID: mdl-28990117
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxygen / Pregnancy Trimester, First / Trophoblasts / Gene Expression Regulation, Enzymologic / Hypoxia-Inducible Factor 1, alpha Subunit / Matrix Metalloproteinase 12 Type of study: Prognostic_studies Limits: Female / Humans / Pregnancy Language: En Journal: Histochem Cell Biol Journal subject: CITOLOGIA / HISTOCITOQUIMICA Year: 2018 Type: Article Affiliation country: Austria
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxygen / Pregnancy Trimester, First / Trophoblasts / Gene Expression Regulation, Enzymologic / Hypoxia-Inducible Factor 1, alpha Subunit / Matrix Metalloproteinase 12 Type of study: Prognostic_studies Limits: Female / Humans / Pregnancy Language: En Journal: Histochem Cell Biol Journal subject: CITOLOGIA / HISTOCITOQUIMICA Year: 2018 Type: Article Affiliation country: Austria