The effect of sulforaphane on oxidative stress and inflammation in rats with toxic hepatitis induced by acetaminophene.

Dokumacioglu, E; Iskender, H; Aktas, M S; Hanedan, B; Dokumacioglu, A; Sen, T M; Musmul, A

Dokumacioglu, E; Iskender, H; Aktas, M S; Hanedan, B; Dokumacioglu, A; Sen, T M; Musmul, A.

Bratisl Lek Listy ; 118(8): 453-459, 2017.

Article in En | MEDLINE | ID: mdl-29050482

Subject(s)

Acetaminophen/toxicity; Analgesics, Non-Narcotic/toxicity; Antioxidants/pharmacology; Chemical and Drug Induced Liver Injury/metabolism; Isothiocyanates/pharmacology; Liver/drug effects; Oxidative Stress/drug effects; Alanine Transaminase/drug effects; Alanine Transaminase/metabolism; Animals; Aspartate Aminotransferases/drug effects; Aspartate Aminotransferases/metabolism; C-Reactive Protein/drug effects; C-Reactive Protein/metabolism; Inflammation; Liver/metabolism; Male; Malondialdehyde/metabolism; Neopterin/metabolism; Plant Extracts/pharmacology; Protective Agents/pharmacology; Rats; Rats, Sprague-Dawley; Sulfoxides

Key words

acetaminophen; lipid peroxidation; neopterin; oxidative stress sulforaphane.

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Isothiocyanates / Oxidative Stress / Analgesics, Non-Narcotic / Chemical and Drug Induced Liver Injury / Liver / Acetaminophen / Antioxidants Type of study: Guideline Limits: Animals Language: En Journal: Bratisl Lek Listy Year: 2017 Type: Article

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