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A vimentin binding small molecule leads to mitotic disruption in mesenchymal cancers.
Bollong, Michael J; Pietilä, Mika; Pearson, Aaron D; Sarkar, Tapasree Roy; Ahmad, Insha; Soundararajan, Rama; Lyssiotis, Costas A; Mani, Sendurai A; Schultz, Peter G; Lairson, Luke L.
Affiliation
  • Bollong MJ; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037.
  • Pietilä M; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Pearson AD; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037.
  • Sarkar TR; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Ahmad I; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037.
  • Soundararajan R; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Lyssiotis CA; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037.
  • Mani SA; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 smani@mdanderson.org schultz@scripps.edu llairson@scripps.edu.
  • Schultz PG; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037; smani@mdanderson.org schultz@scripps.edu llairson@scripps.edu.
  • Lairson LL; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037; smani@mdanderson.org schultz@scripps.edu llairson@scripps.edu.
Proc Natl Acad Sci U S A ; 114(46): E9903-E9912, 2017 11 14.
Article in En | MEDLINE | ID: mdl-29087350

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcoma / Vimentin / Mitosis Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2017 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcoma / Vimentin / Mitosis Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2017 Type: Article