Survival Outcomes in Patients With RAS Wild Type Metastatic Colorectal Cancer Classified According to Köhne Prognostic Category and BRAF Mutation Status.

Siena, Salvatore; Rivera, Fernando; Taieb, Julien; Peeters, Marc; Prenen, Hans; Koukakis, Reija; Demonty, Gaston; Köhne, Claus-Henning

Siena, Salvatore; Rivera, Fernando; Taieb, Julien; Peeters, Marc; Prenen, Hans; Koukakis, Reija; Demonty, Gaston; Köhne, Claus-Henning.

Affiliation

Siena S; Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, and Dipartimento di Oncologia e Emato-Oncologia, Università degli Studi di Milano, Milan, Italy. Electronic address: salvatore.siena@ospedaleniguarda.it.
Rivera F; Hospital Universitario Marqués de Valdecilla, Santander, Spain.
Taieb J; Sorbonne Paris Cité, Paris Descartes University, Georges Pompidou European Hospital, Paris, France.
Peeters M; University Hospital Antwerp, Antwerp, Belgium.
Prenen H; Digestive Oncology Unit, UZ Leuven, Leuven, Belgium.
Koukakis R; Biostatistics, Amgen Ltd, Uxbridge, United Kingdom.
Demonty G; Medical Development, Amgen (Europe) GmbH, Zug, Switzerland.
Köhne CH; Klinikum Oldenburg, Oldenburg, Germany.

Clin Colorectal Cancer ; 17(1): 50-57.e8, 2018 03.

Article in En | MEDLINE | ID: mdl-29096990

Subject(s)

Adenocarcinoma/classification; Adenocarcinoma/mortality; Colorectal Neoplasms/classification; Colorectal Neoplasms/mortality; Adenocarcinoma/drug therapy; Adult; Aged; Antineoplastic Agents, Immunological/therapeutic use; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Camptothecin/analogs & derivatives; Camptothecin/therapeutic use; Clinical Trials, Phase III as Topic; Colorectal Neoplasms/drug therapy; Female; Fluorouracil/therapeutic use; Humans; Kaplan-Meier Estimate; Leucovorin/therapeutic use; Male; Middle Aged; Mutation; Organoplatinum Compounds/therapeutic use; Panitumumab/therapeutic use; Prognosis; Progression-Free Survival; Proto-Oncogene Proteins B-raf/genetics; Retrospective Studies; Treatment Outcome

Key words

Chemotherapy; Overall survival; Panitumumab; Prognosis; Progression-free survival

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Adenocarcinoma Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Clin Colorectal Cancer Journal subject: GASTROENTEROLOGIA / NEOPLASIAS Year: 2018 Type: Article

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