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Pharmacodynamics and proteomic analysis of acalabrutinib therapy: similarity of on-target effects to ibrutinib and rationale for combination therapy.
Patel, V K; Lamothe, B; Ayres, M L; Gay, J; Cheung, J P; Balakrishnan, K; Ivan, C; Morse, J; Nelson, M; Keating, M J; Wierda, W G; Marszalek, J R; Gandhi, V.
Affiliation
  • Patel VK; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Lamothe B; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Ayres ML; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Gay J; Institute of Applied Cancer Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Cheung JP; Acerta Pharma, Redwood City, CA, USA.
  • Balakrishnan K; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Ivan C; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Morse J; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Nelson M; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Keating MJ; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Wierda WG; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Marszalek JR; Institute of Applied Cancer Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Gandhi V; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Leukemia ; 32(4): 920-930, 2018 04.
Article in En | MEDLINE | ID: mdl-29099493
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Antineoplastic Combined Chemotherapy Protocols Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2018 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Antineoplastic Combined Chemotherapy Protocols Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2018 Type: Article Affiliation country: United States