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Pharmacokinetics of the prototype and hydrolyzed carboxylic forms of ginkgolides A, B, and K administered as a ginkgo diterpene lactones meglumine injection in beagle dogs.
Wang, Shu-Yao; A, Ji-Ye; Fei, Fei; Geng, Jian-Liang; Peng, Ying; Ouyang, Bing-Chen; Wang, Pei; Jin, Xiao-Liang; Zhao, Yu-Qing; Wang, Jian-Kun; Geng, Ting; Li, Yan-Jing; Huang, Wen-Zhe; Wang, Zhen-Zhong; Xiao, Wei; Wang, Guang-Ji.
Affiliation
  • Wang SY; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China; Jiangsu Kanion Modern Chinese Medicine Institute, Nanjing 210017, China; State Key Laboratory of Pharmaceutical New-Tech for Chinese Medicine, Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China
  • A JY; Key Lab of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
  • Fei F; Key Lab of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
  • Geng JL; Key Lab of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
  • Peng Y; Key Lab of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
  • Ouyang BC; Key Lab of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
  • Wang P; Key Lab of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
  • Jin XL; Key Lab of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
  • Zhao YQ; Key Lab of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
  • Wang JK; Key Lab of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
  • Geng T; Jiangsu Kanion Modern Chinese Medicine Institute, Nanjing 210017, China; State Key Laboratory of Pharmaceutical New-Tech for Chinese Medicine, Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China.
  • Li YJ; Jiangsu Kanion Modern Chinese Medicine Institute, Nanjing 210017, China; State Key Laboratory of Pharmaceutical New-Tech for Chinese Medicine, Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China.
  • Huang WZ; Jiangsu Kanion Modern Chinese Medicine Institute, Nanjing 210017, China; State Key Laboratory of Pharmaceutical New-Tech for Chinese Medicine, Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China.
  • Wang ZZ; Jiangsu Kanion Modern Chinese Medicine Institute, Nanjing 210017, China; State Key Laboratory of Pharmaceutical New-Tech for Chinese Medicine, Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China.
  • Xiao W; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China; Jiangsu Kanion Modern Chinese Medicine Institute, Nanjing 210017, China; State Key Laboratory of Pharmaceutical New-Tech for Chinese Medicine, Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China
  • Wang GJ; Key Lab of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China. Electronic address: guangjiwang@hotmail.com.
Chin J Nat Med ; 15(10): 775-784, 2017 Oct.
Article in En | MEDLINE | ID: mdl-29103463
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plant Extracts / Ginkgo biloba / Ginkgolides / Lactones Limits: Animals Language: En Journal: Chin J Nat Med Year: 2017 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plant Extracts / Ginkgo biloba / Ginkgolides / Lactones Limits: Animals Language: En Journal: Chin J Nat Med Year: 2017 Type: Article Affiliation country: China