In vitro characterization of the human cytochrome P-450 involved in polymorphic oxidation of propafenone.

Kroemer, H K; Mikus, G; Kronbach, T; Meyer, U A; Eichelbaum, M

Kroemer, H K; Mikus, G; Kronbach, T; Meyer, U A; Eichelbaum, M.

Affiliation

Kroemer HK; Dr. Margarete-Fischer-Bosch Institut für Klinische Pharmakologie, Stuttgart, Federal Republic of Germany.

Clin Pharmacol Ther ; 45(1): 28-33, 1989 Jan.

Article in En | MEDLINE | ID: mdl-2910635

Subject(s)

Cytochrome P-450 Enzyme System/physiology; Propafenone/metabolism; Autoantibodies/immunology; Dealkylation; Ethanolamines/metabolism; Humans; Hydroxylation; In Vitro Techniques; Microsomes, Liver/metabolism; Polymorphism, Genetic; Stereoisomerism

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Collection: 01-internacional Database: MEDLINE Main subject: Propafenone / Cytochrome P-450 Enzyme System Limits: Humans Language: En Journal: Clin Pharmacol Ther Year: 1989 Type: Article

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