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Selenium-containing analogues of WC-9 are extremely potent inhibitors of Trypanosoma cruzi proliferation.
Chao, María N; Storey, Melissa; Li, Catherine; Rodríguez, Maricel G; Di Salvo, Florencia; Szajnman, Sergio H; Moreno, Silvia N J; Docampo, Roberto; Rodriguez, Juan B.
Affiliation
  • Chao MN; Departamento de Química Orgánica and UMYMFOR (CONICET-FCEyN), Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón 2, Ciudad Universitaria, C1428EHA Buenos Aires, Argentina.
  • Storey M; Center for Tropical and Emerging Global Diseases and Department of Cellular Biology, University of Georgia, Athens, GA 30602, USA.
  • Li C; Center for Tropical and Emerging Global Diseases and Department of Cellular Biology, University of Georgia, Athens, GA 30602, USA.
  • Rodríguez MG; Departamento de Química Inorgánica, Analítica y Química Física/INQUIMAE-CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón 2, Buenos Aires C1428EGA, Argentina.
  • Di Salvo F; Departamento de Química Inorgánica, Analítica y Química Física/INQUIMAE-CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón 2, Buenos Aires C1428EGA, Argentina.
  • Szajnman SH; Departamento de Química Orgánica and UMYMFOR (CONICET-FCEyN), Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón 2, Ciudad Universitaria, C1428EHA Buenos Aires, Argentina.
  • Moreno SNJ; Center for Tropical and Emerging Global Diseases and Department of Cellular Biology, University of Georgia, Athens, GA 30602, USA.
  • Docampo R; Center for Tropical and Emerging Global Diseases and Department of Cellular Biology, University of Georgia, Athens, GA 30602, USA.
  • Rodriguez JB; Departamento de Química Orgánica and UMYMFOR (CONICET-FCEyN), Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón 2, Ciudad Universitaria, C1428EHA Buenos Aires, Argentina. Electronic address: jbr@qo.fcen.uba.ar.
Bioorg Med Chem ; 25(24): 6435-6449, 2017 12 15.
Article in En | MEDLINE | ID: mdl-29107437
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenyl Ethers / Selenium / Thiocyanates / Trypanocidal Agents / Trypanosoma cruzi Limits: Animals Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2017 Type: Article Affiliation country: Argentina
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenyl Ethers / Selenium / Thiocyanates / Trypanocidal Agents / Trypanosoma cruzi Limits: Animals Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2017 Type: Article Affiliation country: Argentina