Hypoxia due to positive pressure ventilation in Edwards' syndrome: A case report.
J Int Med Res
; 46(2): 895-900, 2018 Feb.
Article
in En
| MEDLINE
| ID: mdl-29125001
ABSTRACT
Edwards' syndrome also known as trisomy 18 is a congenital disorder associated with cardiovascular issues including ventricular septal defect (VSD), atrial septal defect (ASD) and patent duct arteriosus (PDA). An emergency colostomy was performed on a neonate born with an imperforate anus. Pre-operative transthoracic echocardiography showed presence of VSD, a patent foramen ovale (PFO) or ASD. Even though the baby had a good general condition and optimal peripheral oxygen saturation (SpO2), during positive pressure ventilation, she suffered severe hypoxia (50% SpO2). The cause of the hypoxia was thought to be the right-left shunt and so during a second attempt at anaesthesia a vasopressor (noradrenaline 0.03 µg/kg/min) was infused to increase systemic vascular resistance. Thereafter, SpO2 increased to 80-90% and the surgery was completed. The baby recovered without any neurological complications. Genetic testing post-partum showed she had Edwards' syndrome.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Anus, Imperforate
/
Positive-Pressure Respiration
/
Trisomy 18 Syndrome
/
Heart Septal Defects, Ventricular
/
Hypoxia
Type of study:
Etiology_studies
Limits:
Female
/
Humans
/
Newborn
Language:
En
Journal:
J Int Med Res
Year:
2018
Type:
Article