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The tumor suppressor phosphatase PP2A-B56α regulates stemness and promotes the initiation of malignancies in a novel murine model.
Janghorban, Mahnaz; Langer, Ellen M; Wang, Xiaoyan; Zachman, Derek; Daniel, Colin J; Hooper, Jody; Fleming, William H; Agarwal, Anupriya; Sears, Rosalie C.
Affiliation
  • Janghorban M; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, Oregon, United States of America.
  • Langer EM; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, Oregon, United States of America.
  • Wang X; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, Oregon, United States of America.
  • Zachman D; Papé Family Pediatric Research Institute, Oregon Stem Cell Center, Department of Pediatrics, Portland, Oregon, United States of America.
  • Daniel CJ; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, Oregon, United States of America.
  • Hooper J; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
  • Fleming WH; Papé Family Pediatric Research Institute, Oregon Stem Cell Center, Department of Pediatrics, Portland, Oregon, United States of America.
  • Agarwal A; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
  • Sears RC; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
PLoS One ; 12(11): e0188910, 2017.
Article in En | MEDLINE | ID: mdl-29190822
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Protein Phosphatase 2 / Neoplasms, Experimental Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2017 Type: Article Affiliation country: United States
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Protein Phosphatase 2 / Neoplasms, Experimental Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2017 Type: Article Affiliation country: United States