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TGF-ß synergizes with ML264 to block IL-1ß-induced matrix degradation mediated by Krüppel-like factor 5 in the nucleus pulposus.
Xie, Ziang; Jie, Zhiwei; Wang, Gangliang; Sun, Xuewu; Tang, Pan; Chen, Shuai; Qin, An; Wang, Jian; Fan, Shunwu.
Affiliation
  • Xie Z; Department of Orthopaedics, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China; Key Laboratory of Biotherapy of Zhejiang Province, Hangzhou, China.
  • Jie Z; Department of Orthopaedics, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China; Key Laboratory of Biotherapy of Zhejiang Province, Hangzhou, China.
  • Wang G; Department of Orthopaedics, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China; Key Laboratory of Biotherapy of Zhejiang Province, Hangzhou, China.
  • Sun X; Department of Orthopaedics, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China; Key Laboratory of Biotherapy of Zhejiang Province, Hangzhou, China.
  • Tang P; Department of Orthopaedics, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China; Key Laboratory of Biotherapy of Zhejiang Province, Hangzhou, China.
  • Chen S; Department of Orthopaedics, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
  • Qin A; Department of Orthopaedics, Shanghai Key Laboratory of Orthopaedic Implant, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200011, China.
  • Wang J; Department of Orthopedics, Tongde Hospital of Zhejiang Province, Hangzhou, China. Electronic address: hztdwangjian@163.com.
  • Fan S; Department of Orthopaedics, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China. Electronic address: shunwu_fan@zju.edu.cn.
Biochim Biophys Acta Mol Basis Dis ; 1864(2): 579-589, 2018 Feb.
Article in En | MEDLINE | ID: mdl-29196238
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acrylamides / Cyclic S-Oxides / Kruppel-Like Transcription Factors / Interleukin-1beta / Transforming Growth Factor beta1 / Nucleus Pulposus Limits: Animals / Humans / Male Language: En Journal: Biochim Biophys Acta Mol Basis Dis Year: 2018 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acrylamides / Cyclic S-Oxides / Kruppel-Like Transcription Factors / Interleukin-1beta / Transforming Growth Factor beta1 / Nucleus Pulposus Limits: Animals / Humans / Male Language: En Journal: Biochim Biophys Acta Mol Basis Dis Year: 2018 Type: Article Affiliation country: China