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2',4-Dihydroxy-3',4',6'-trimethoxychalcone from Chromolaena odorata possesses anti-inflammatory effects via inhibition of NF-κB and p38 MAPK in lipopolysaccharide-activated RAW 264.7 macrophages.
Dhar, Rana; Kimseng, Rungruedee; Chokchaisiri, Ratchanaporn; Hiransai, Poonsit; Utaipan, Tanyarath; Suksamrarn, Apichart; Chunglok, Warangkana.
Affiliation
  • Dhar R; a School of Allied Health Sciences , Walailak University , Nakhon Si Thammarat , Thailand.
  • Kimseng R; a School of Allied Health Sciences , Walailak University , Nakhon Si Thammarat , Thailand.
  • Chokchaisiri R; b Department of Chemistry, School of Science , University of Phayao , Phayao , Thailand.
  • Hiransai P; a School of Allied Health Sciences , Walailak University , Nakhon Si Thammarat , Thailand.
  • Utaipan T; c Department of Pre-Clinic, Faculty of Science and Technology , Prince of Songkla University, Pattani Campus , Pattani , Thailand.
  • Suksamrarn A; d Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science , Ramkhamhaeng University , Bangkok , Thailand.
  • Chunglok W; a School of Allied Health Sciences , Walailak University , Nakhon Si Thammarat , Thailand.
Immunopharmacol Immunotoxicol ; 40(1): 43-51, 2018 Feb.
Article in En | MEDLINE | ID: mdl-29199487
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anti-Inflammatory Agents, Non-Steroidal / Lipopolysaccharides / NF-kappa B / MAP Kinase Signaling System / Chromolaena / Chalcones / P38 Mitogen-Activated Protein Kinases / Macrophage Activation / Macrophages Limits: Animals Language: En Journal: Immunopharmacol Immunotoxicol Journal subject: ALERGIA E IMUNOLOGIA / FARMACOLOGIA / TOXICOLOGIA Year: 2018 Type: Article Affiliation country: Thailand
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anti-Inflammatory Agents, Non-Steroidal / Lipopolysaccharides / NF-kappa B / MAP Kinase Signaling System / Chromolaena / Chalcones / P38 Mitogen-Activated Protein Kinases / Macrophage Activation / Macrophages Limits: Animals Language: En Journal: Immunopharmacol Immunotoxicol Journal subject: ALERGIA E IMUNOLOGIA / FARMACOLOGIA / TOXICOLOGIA Year: 2018 Type: Article Affiliation country: Thailand