[Humanization of Murine Monoclonal anti-hTNF Antibody: The F10 Story].

Efimov, G A; Raats, J M H; Chirivi, R G S; van Rosmalen, J W G; Nedospasov, S A

Efimov, G A; Raats, J M H; Chirivi, R G S; van Rosmalen, J W G; Nedospasov, S A.

Affiliation

Efimov GA; National Research Center for Hematology, Ministry of Healthcare of the Russian Federation, Moscow, 125167 Russia.
Raats JMH; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.
Chirivi RGS; Moscow State University, Moscow, 119991 Russia.
van Rosmalen JWG; ModiQuest B.V., 5349 AE Oss The Netherlands.
Nedospasov SA; ModiQuest B.V., 5349 AE Oss The Netherlands.

Mol Biol (Mosk) ; 51(6): 1062-1068, 2017.

Article in Ru | MEDLINE | ID: mdl-29271968

Subject(s)

Adalimumab/biosynthesis; Antibodies, Monoclonal, Humanized/biosynthesis; Antibodies, Monoclonal/biosynthesis; Arthritis, Rheumatoid/drug therapy; Infliximab/biosynthesis; Tumor Necrosis Factor-alpha/antagonists & inhibitors; Adalimumab/isolation & purification; Adalimumab/pharmacology; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal/history; Antibodies, Monoclonal/isolation & purification; Antibodies, Monoclonal/pharmacology; Antibodies, Monoclonal, Humanized/history; Antibodies, Monoclonal, Humanized/isolation & purification; Antibodies, Monoclonal, Humanized/pharmacology; Arthritis, Rheumatoid/genetics; Arthritis, Rheumatoid/immunology; Arthritis, Rheumatoid/pathology; Cloning, Molecular; Gene Expression; History, 20th Century; History, 21st Century; Humans; Infliximab/isolation & purification; Infliximab/pharmacology; Mice; Psoriasis/drug therapy; Psoriasis/genetics; Psoriasis/immunology; Psoriasis/pathology; Spondylitis, Ankylosing/drug therapy; Spondylitis, Ankylosing/genetics; Spondylitis, Ankylosing/immunology; Spondylitis, Ankylosing/pathology; Tumor Necrosis Factor-alpha/genetics; Tumor Necrosis Factor-alpha/immunology

Key words

TNF; humanized antibodies; recombinant antibodies; tumor necrosis factor

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Tumor Necrosis Factor-alpha / Antibodies, Monoclonal, Humanized / Adalimumab / Infliximab / Antibodies, Monoclonal Language: Ru Journal: Mol Biol (Mosk) Year: 2017 Type: Article

Fulltext

XML

PubMed Links

Search on Google