The human microbiome in evolution.
BMC Biol
; 15(1): 127, 2017 12 27.
Article
in En
| MEDLINE
| ID: mdl-29282061
ABSTRACT
The trillions of microbes living in the gut-the gut microbiota-play an important role in human biology and disease. While much has been done to explore its diversity, a full understanding of our microbiomes demands an evolutionary perspective. In this review, we compare microbiomes from human populations, placing them in the context of microbes from humanity's near and distant animal relatives. We discuss potential mechanisms to generate host-specific microbiome configurations and the consequences of disrupting those configurations. Finally, we propose that this broader phylogenetic perspective is useful for understanding the mechanisms underlying human-microbiome interactions.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Biological Evolution
/
Microbiota
Limits:
Animals
/
Humans
Language:
En
Journal:
BMC Biol
Journal subject:
BIOLOGIA
Year:
2017
Type:
Article
Affiliation country:
United States