Extending Genome-Wide Association Study Results to Test Classic Anthropological Hypotheses: Human Third Molar Agenesis and the "Probable Mutation Effect".

Vukelic, Adrijana; Cohen, Jacob A; Sullivan, Alexis P; Perry, George H

Vukelic, Adrijana; Cohen, Jacob A; Sullivan, Alexis P; Perry, George H.

Affiliation

Vukelic A; 1 Department of Anthropology, Pennsylvania State University, University Park, Pennsylvania, USA.
Cohen JA; 2 Department of Biology, Pennsylvania State University, University Park, Pennsylvania, USA.
Sullivan AP; 2 Department of Biology, Pennsylvania State University, University Park, Pennsylvania, USA.
Perry GH; 2 Department of Biology, Pennsylvania State University, University Park, Pennsylvania, USA.

Hum Biol ; 89(2): 157-169, 2017 04.

Article in En | MEDLINE | ID: mdl-29299963

Subject(s)

Anodontia/epidemiology; Genome-Wide Association Study/methods; Molar, Third/abnormalities; Tooth, Impacted/genetics; Adult; Animals; Anodontia/history; Anthropology/history; Biological Evolution; Brain/anatomy & histology; Facial Bones/anatomy & histology; Genetics, Population/history; Genomics/methods; History, Ancient; Hominidae/genetics; Humans; Japan/epidemiology; Mutation; Phenotype; Polymorphism, Single Nucleotide/genetics; Probability; Republic of Korea/epidemiology

Key words

anthropometric traits; evolutionary genomics; gwasw; human dental formula evolution; wisdom tooth

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PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Tooth, Impacted / Genome-Wide Association Study / Anodontia / Molar, Third Type of study: Prognostic_studies / Risk_factors_studies Limits: Adult / Animals / Humans Country/Region as subject: Asia Language: En Journal: Hum Biol Year: 2017 Type: Article Affiliation country: United States

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