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Symmetric dimeric bisbenzimidazoles DBP(n) reduce methylation of RARB and PTEN while significantly increase methylation of rRNA genes in MCF-7 cancer cells.
Kostyuk, Svetlana V; Kvasha, Margarita A; Khrabrova, Daria A; Kirsanova, Olga V; Ershova, Elizaveta S; Malinovskaya, Elena M; Veiko, Natalia N; Ivanov, Alexander A; Koval, Vasiliy S; Zhuze, Alexei L; Tashlitsky, Vadim H; Umriukhin, Pavel E; Kutsev, Sergey I; Gromova, Elizaveta S.
Affiliation
  • Kostyuk SV; Research Centre for Medical Genetics, Moscow, Russia.
  • Kvasha MA; Chemistry Department, Moscow State University, Moscow, Russia.
  • Khrabrova DA; Chemistry Department, Moscow State University, Moscow, Russia.
  • Kirsanova OV; Chemistry Department, Moscow State University, Moscow, Russia.
  • Ershova ES; Research Centre for Medical Genetics, Moscow, Russia.
  • Malinovskaya EM; Research Centre for Medical Genetics, Moscow, Russia.
  • Veiko NN; Research Centre for Medical Genetics, Moscow, Russia.
  • Ivanov AA; N.N. Blokhin Russian Cancer Research Center, Moscow, Russia.
  • Koval VS; Engelhardt Institute of Molecular Biology, Moscow, Russia.
  • Zhuze AL; Engelhardt Institute of Molecular Biology, Moscow, Russia.
  • Tashlitsky VH; Chemistry Department, Moscow State University, Moscow, Russia.
  • Umriukhin PE; I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
  • Kutsev SI; P.K. Anokhin Institute of Normal Physiology, Moscow, Russia.
  • Gromova ES; Chemistry Department, Moscow State University, Moscow, Russia.
PLoS One ; 13(1): e0189826, 2018.
Article in En | MEDLINE | ID: mdl-29329300
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / RNA, Ribosomal / Receptors, Retinoic Acid / DNA Methylation Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2018 Type: Article Affiliation country: RUSSIA
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / RNA, Ribosomal / Receptors, Retinoic Acid / DNA Methylation Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2018 Type: Article Affiliation country: RUSSIA