Sirolimus-induced regression of a large orbital lymphangioma.
Orbit
; 38(1): 79-80, 2019 Feb.
Article
in En
| MEDLINE
| ID: mdl-29405800
ABSTRACT
Microcystic lymphatic malformations are difficult to treat surgically, especially when located in the orbital apex. Recently, pharmacologic inhibition of the mTOR pathway by sirolimus was reported as a safe and efficacious treatment option for lymphatic malformations (also known as lymphangiomas). We report the case of a young male patient in which a unilateral, retrobulbar lymphatic malformation regressed to a large extent under treatment with 1 mg sirolimus given orally twice a day over a period of six months.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Orbital Neoplasms
/
Sirolimus
/
Lymphangioma
/
Antibiotics, Antineoplastic
Limits:
Adult
/
Humans
/
Male
Language:
En
Journal:
Orbit
Year:
2019
Type:
Article
Affiliation country:
Germany