New perspectives on the computational characterization of the kinetics of binding-unbinding in drug design: implications for novel therapies.

Moreno-Vargas, Liliana M; Prada-Gracia, Diego

Moreno-Vargas, Liliana M; Prada-Gracia, Diego.

Affiliation

Moreno-Vargas LM; Unidad de Investigación en Enfermedades Oncológicas, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
Prada-Gracia D; Department of Pharmacological Sciences, Icahn Medical Institute Building, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: prada.gracia@gmail.com.

Bol Med Hosp Infant Mex ; 73(6): 424-431, 2016.

Article in En | MEDLINE | ID: mdl-29421287

Key words

Binding kinetics; Cinética de unión; Computer-Aided Drug Design; Dinámica de simulación molecular; Diseño de fármacos asistido por ordenador; Drug-target residence time; Molecular Dynamics Simulation; Tiempo de residencia fármaco-diana

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Bol Med Hosp Infant Mex Year: 2016 Type: Article Affiliation country: Mexico

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Bol Med Hosp Infant Mex Year: 2016 Type: Article Affiliation country: Mexico