Amyloid-ß with isomerized Asp7 cytotoxicity is coupled to protein phosphorylation.

Zatsepina, O G; Kechko, O I; Mitkevich, V A; Kozin, S A; Yurinskaya, M M; Vinokurov, M G; Serebryakova, M V; Rezvykh, A P; Evgen'ev, M B; Makarov, A A

Zatsepina, O G; Kechko, O I; Mitkevich, V A; Kozin, S A; Yurinskaya, M M; Vinokurov, M G; Serebryakova, M V; Rezvykh, A P; Evgen'ev, M B; Makarov, A A.

Affiliation

Zatsepina OG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Kechko OI; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Mitkevich VA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Kozin SA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Yurinskaya MM; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Vinokurov MG; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia.
Serebryakova MV; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia.
Rezvykh AP; A.N. Belozersky Institute of Physico-Chemical Biology MSU, Moscow, Russia.
Evgen'ev MB; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Makarov AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.

Sci Rep ; 8(1): 3518, 2018 02 23.

Article in En | MEDLINE | ID: mdl-29476081

Subject(s)

Amyloid beta-Peptides/toxicity; Aspartic Acid/metabolism; Neurons/drug effects; Peptide Fragments/toxicity; Phosphoserine/metabolism; Protein Processing, Post-Translational; tau Proteins/metabolism; Alzheimer Disease/genetics; Alzheimer Disease/metabolism; Alzheimer Disease/pathology; Apoptosis/drug effects; Cell Line, Tumor; Cell Survival/drug effects; Electrophoresis, Gel, Two-Dimensional; Humans; Models, Biological; Neurons/metabolism; Neurons/pathology; Nuclear Matrix-Associated Proteins/genetics; Nuclear Matrix-Associated Proteins/metabolism; Phosphorylation; Protein Isoforms/toxicity; RNA-Binding Proteins/genetics; RNA-Binding Proteins/metabolism; Tubulin/genetics; Tubulin/metabolism; tau Proteins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Phosphoserine / Protein Processing, Post-Translational / Amyloid beta-Peptides / Tau Proteins / Aspartic Acid / Neurons Type of study: Prognostic_studies Limits: Humans Language: En Journal: Sci Rep Year: 2018 Type: Article Affiliation country: RUSSIA

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