SUMO targets the APC/C to regulate transition from metaphase to anaphase.

Eifler, Karolin; Cuijpers, Sabine A G; Willemstein, Edwin; Raaijmakers, Jonne A; El Atmioui, Dris; Ovaa, Huib; Medema, René H; Vertegaal, Alfred C O

Eifler, Karolin; Cuijpers, Sabine A G; Willemstein, Edwin; Raaijmakers, Jonne A; El Atmioui, Dris; Ovaa, Huib; Medema, René H; Vertegaal, Alfred C O.

Affiliation

Eifler K; Department of Molecular Cell Biology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, The Netherlands. k.eifler-olivi@imb-mainz.de.
Cuijpers SAG; Institute of Molecular Biology gGmbH, Ackermannweg 4, Mainz, 55128, Germany. k.eifler-olivi@imb-mainz.de.
Willemstein E; Department of Molecular Cell Biology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, The Netherlands.
Raaijmakers JA; Department of Molecular Cell Biology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, The Netherlands.
El Atmioui D; Oncode Institute and Division of Cell Biology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, 1066 CX, The Netherlands.
Ovaa H; Oncode Institute and Department of Chemical Immunology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, The Netherlands.
Medema RH; Oncode Institute and Department of Chemical Immunology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, The Netherlands.
Vertegaal ACO; Oncode Institute and Division of Cell Biology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, 1066 CX, The Netherlands.

Nat Commun ; 9(1): 1119, 2018 03 16.

Article in En | MEDLINE | ID: mdl-29549242

Subject(s)

Apc4 Subunit, Anaphase-Promoting Complex-Cyclosome/metabolism; Mitosis/genetics; Small Ubiquitin-Related Modifier Proteins/metabolism; Sumoylation/genetics; Ubiquitins/metabolism; Apc4 Subunit, Anaphase-Promoting Complex-Cyclosome/genetics; Cell Line, Tumor; HCT116 Cells; HeLa Cells; Humans; Kinesins/metabolism; RNA Interference; RNA, Small Interfering/genetics; Signal Transduction/physiology; Small Ubiquitin-Related Modifier Proteins/genetics; Ubiquitin-Activating Enzymes/genetics; Ubiquitination/genetics; Ubiquitins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ubiquitins / Small Ubiquitin-Related Modifier Proteins / Sumoylation / Apc4 Subunit, Anaphase-Promoting Complex-Cyclosome / Mitosis Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2018 Type: Article Affiliation country: Netherlands

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