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TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis.
Deshaies, Jade-Emmanuelle; Shkreta, Lulzim; Moszczynski, Alexander J; Sidibé, Hadjara; Semmler, Sabrina; Fouillen, Aurélien; Bennett, Estelle R; Bekenstein, Uriya; Destroismaisons, Laurie; Toutant, Johanne; Delmotte, Quentin; Volkening, Kathryn; Stabile, Stéphanie; Aulas, Anaïs; Khalfallah, Yousra; Soreq, Hermona; Nanci, Antonio; Strong, Michael J; Chabot, Benoit; Vande Velde, Christine.
Affiliation
  • Deshaies JE; Department of Neurosciences, Université de Montréal, Montréal, QC, Canada.
  • Shkreta L; CHUM Research Center, Montréal, QC, Canada.
  • Moszczynski AJ; Department of Microbiology and Infectious Diseases, Université de Sherbrooke, Sherbrooke, QC, Canada.
  • Sidibé H; Molecular Medicine Research Group, Robarts Research Institute, London, ON, Canada.
  • Semmler S; Department of Clinical Neurological Sciences, Western University, London, ON, Canada.
  • Fouillen A; Department of Neurosciences, Université de Montréal, Montréal, QC, Canada.
  • Bennett ER; CHUM Research Center, Montréal, QC, Canada.
  • Bekenstein U; CHUM Research Center, Montréal, QC, Canada.
  • Destroismaisons L; Department of Neurology and Neurosurgery, McGill University, Montréal, QC, Canada.
  • Toutant J; Department of Stomatology, Université de Montréal, Montréal, QC, Canada.
  • Delmotte Q; The Alexander Silberman Institute of Life Sciences, The Edmond and Lily Safra Center of Brain Science, The Hebrew University of Jerusalem, Israel.
  • Volkening K; The Alexander Silberman Institute of Life Sciences, The Edmond and Lily Safra Center of Brain Science, The Hebrew University of Jerusalem, Israel.
  • Stabile S; Department of Biological Chemistry, The Hebrew University of Jerusalem, Israel.
  • Aulas A; CHUM Research Center, Montréal, QC, Canada.
  • Khalfallah Y; Department of Microbiology and Infectious Diseases, Université de Sherbrooke, Sherbrooke, QC, Canada.
  • Soreq H; CHUM Research Center, Montréal, QC, Canada.
  • Nanci A; Molecular Medicine Research Group, Robarts Research Institute, London, ON, Canada.
  • Strong MJ; Department of Clinical Neurological Sciences, Western University, London, ON, Canada.
  • Chabot B; Department of Neurosciences, Université de Montréal, Montréal, QC, Canada.
  • Vande Velde C; CHUM Research Center, Montréal, QC, Canada.
Brain ; 141(5): 1320-1333, 2018 05 01.
Article in En | MEDLINE | ID: mdl-29562314
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alternative Splicing / DNA-Binding Proteins / Protein Aggregation, Pathological / Heterogeneous Nuclear Ribonucleoprotein A1 / Amyotrophic Lateral Sclerosis Limits: Humans Language: En Journal: Brain Year: 2018 Type: Article Affiliation country: Canada
Fulltext
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PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alternative Splicing / DNA-Binding Proteins / Protein Aggregation, Pathological / Heterogeneous Nuclear Ribonucleoprotein A1 / Amyotrophic Lateral Sclerosis Limits: Humans Language: En Journal: Brain Year: 2018 Type: Article Affiliation country: Canada