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Stem Cells Therapy for Spinal Cord Injury.
Gazdic, Marina; Volarevic, Vladislav; Harrell, C Randall; Fellabaum, Crissy; Jovicic, Nemanja; Arsenijevic, Nebojsa; Stojkovic, Miodrag.
Affiliation
  • Gazdic M; Faculty of Medical Sciences, Department of Genetics, University of Kragujevac, 34000 Kragujevac, Serbia. marinagazdic87@gmail.com.
  • Volarevic V; Faculty of Medical Sciences, Department of Microbiology and immunology, Center for Molecular Medicine and Stem Cell Research, University of Kragujevac, 34000 Kragujevac, Serbia. drvolarevic@yahoo.com.
  • Harrell CR; Regenerative Processing Plant, LLC, 34176 US Highway 19 N Palm Harbor, Palm Harbor, FL 34684, USA. dr.harrell@regenerativeplant.org.
  • Fellabaum C; Regenerative Processing Plant, LLC, 34176 US Highway 19 N Palm Harbor, Palm Harbor, FL 34684, USA. crissy@regenerativeplant.org.
  • Jovicic N; Faculty of Medical Sciences, Department of Histology and embryology, University of Kragujevac, 34000 Kragujevac, Serbia. nemanjajovicic.kg@gmail.com.
  • Arsenijevic N; Faculty of Medical Sciences, Department of Microbiology and immunology, Center for Molecular Medicine and Stem Cell Research, University of Kragujevac, 34000 Kragujevac, Serbia. arne@medf.kg.ac.rs.
  • Stojkovic M; Faculty of Medical Sciences, Department of Genetics, University of Kragujevac, 34000 Kragujevac, Serbia. mstojkovic@spebo.com.
Int J Mol Sci ; 19(4)2018 Mar 30.
Article in En | MEDLINE | ID: mdl-29601528
Spinal cord injury (SCI), a serious public health issue, most likely occurs in previously healthy young adults. Current therapeutic strategies for SCI includes surgical decompression and pharmacotherapy, however, there is still no gold standard for the treatment of this devastating condition. Inefficiency and adverse effects of standard therapy indicate that novel therapeutic strategies are required. Because of their neuroregenerative and neuroprotective properties, stem cells are a promising tool for the treatment of SCI. Herein, we summarize and discuss the promising therapeutic potential of human embryonic stem cells (hESC), induced pluripotent stem cells (iPSC) and ependymal stem/progenitor cells (epSPC) for SCI.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Cord Injuries / Stem Cell Transplantation Limits: Animals / Humans Language: En Journal: Int J Mol Sci Year: 2018 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Cord Injuries / Stem Cell Transplantation Limits: Animals / Humans Language: En Journal: Int J Mol Sci Year: 2018 Type: Article