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Designer nuclease-mediated gene correction via homology-directed repair in an in vitro model of canine hemophilia B.
Bergmann, Thorsten; Ehrke-Schulz, Eric; Gao, Jian; Schiwon, Maren; Schildgen, Verena; David, Stephan; Schildgen, Oliver; Ehrhardt, Anja.
Affiliation
  • Bergmann T; Institute of Virology and Microbiology, Center for Biomedical Education and Research (ZBAF), Department of Human Medicine, Faculty of Health, Witten/Herdecke University, Witten, Germany.
  • Ehrke-Schulz E; Institute of Virology and Microbiology, Center for Biomedical Education and Research (ZBAF), Department of Human Medicine, Faculty of Health, Witten/Herdecke University, Witten, Germany.
  • Gao J; Institute of Virology and Microbiology, Center for Biomedical Education and Research (ZBAF), Department of Human Medicine, Faculty of Health, Witten/Herdecke University, Witten, Germany.
  • Schiwon M; Institute of Virology and Microbiology, Center for Biomedical Education and Research (ZBAF), Department of Human Medicine, Faculty of Health, Witten/Herdecke University, Witten, Germany.
  • Schildgen V; Institute of Molecular Pathology, Hospital Merheim, Clinics of Cologne, Witten/Herdecke University, Cologne, Germany.
  • David S; Institute of Virology and Microbiology, Center for Biomedical Education and Research (ZBAF), Department of Human Medicine, Faculty of Health, Witten/Herdecke University, Witten, Germany.
  • Schildgen O; Institute of Molecular Pathology, Hospital Merheim, Clinics of Cologne, Witten/Herdecke University, Cologne, Germany.
  • Ehrhardt A; Institute of Virology and Microbiology, Center for Biomedical Education and Research (ZBAF), Department of Human Medicine, Faculty of Health, Witten/Herdecke University, Witten, Germany.
J Gene Med ; 20(5): e3020, 2018 05.
Article in En | MEDLINE | ID: mdl-29608237
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Factor IX / Hemophilia B / Gene Targeting / Dog Diseases / Endonucleases / DNA Breaks, Double-Stranded / Recombinational DNA Repair Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Gene Med Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2018 Type: Article Affiliation country: Germany
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Factor IX / Hemophilia B / Gene Targeting / Dog Diseases / Endonucleases / DNA Breaks, Double-Stranded / Recombinational DNA Repair Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Gene Med Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2018 Type: Article Affiliation country: Germany