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Phase 1b investigation of the MEK inhibitor binimetinib in patients with advanced or metastatic biliary tract cancer.
Finn, R S; Ahn, D H; Javle, M M; Tan, B R; Weekes, C D; Bendell, J C; Patnaik, A; Khan, G N; Laheru, D; Chavira, R; Christy-Bittel, J; Barrett, E; Sawyer, M B; Bekaii-Saab, Tanios S.
Affiliation
  • Finn RS; Department of Medicine, University of California Los Angeles Medical Center, 2020 Santa Monica Blvd, Santa Monica, CA, 90404, USA.
  • Ahn DH; Department of Medicine, Mayo Clinic, 5881 E Mayo Blvd, Phoenix, AZ, 85054, USA.
  • Javle MM; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit #426, Houston, TX, 77030, USA.
  • Tan BR; Department of Medicine, Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8056, St. Louis, MO, 63110, USA.
  • Weekes CD; Department of Medicine, University of Colorado Cancer Center, 12801 E 17th Ave, Aurora, CO, 80045, USA.
  • Bendell JC; Drug Development Program, Sarah Cannon Research Institute/Tennessee Oncology, 250 25th Ave N, Nashville, TN, 37203, USA.
  • Patnaik A; START - South Texas Accelerated Research Therapeutics, 4383 Medical Dr, San Antonio, TX, 78229, USA.
  • Khan GN; Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI, 48202, USA.
  • Laheru D; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 401 N Broadway, Baltimore, MD, 21287, USA.
  • Chavira R; Array BioPharma Inc., 3200 Walnut St, Boulder, CO, 80301, USA.
  • Christy-Bittel J; Array BioPharma Inc., 3200 Walnut St, Boulder, CO, 80301, USA.
  • Barrett E; Array BioPharma Inc., 3200 Walnut St, Boulder, CO, 80301, USA.
  • Sawyer MB; Cross Cancer Institute Department of Medical Oncology, University of Alberta, 11560 University Ave, Edmonton, AB, T6G 1Z2, Canada.
  • Bekaii-Saab TS; Department of Medicine, Mayo Clinic, 5881 E Mayo Blvd, Phoenix, AZ, 85054, USA. bekaii-saab.tanios@mayo.edu.
Invest New Drugs ; 36(6): 1037-1043, 2018 12.
Article in En | MEDLINE | ID: mdl-29785570

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / Biliary Tract Neoplasms / Protein Kinase Inhibitors Type of study: Clinical_trials / Observational_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Invest New Drugs Year: 2018 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / Biliary Tract Neoplasms / Protein Kinase Inhibitors Type of study: Clinical_trials / Observational_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Invest New Drugs Year: 2018 Type: Article Affiliation country: United States