Up-regulation of regulatory T cells, CD200 and TIM3 expression in cytogenetically normal acute myeloid leukemia.

Zahran, Asmaa M; Mohammed Saleh, Mostafa F; Sayed, Mona M; Rayan, Amal; Ali, Arwa Mohammed; Hetta, Helal F

Zahran, Asmaa M; Mohammed Saleh, Mostafa F; Sayed, Mona M; Rayan, Amal; Ali, Arwa Mohammed; Hetta, Helal F.

Affiliation

Zahran AM; Clinical Pathology Department, South Egypt Cancer Institute, Assiut University, Assiut, Egypt.
Mohammed Saleh MF; Clinical Hematology Unit, Internal Medicine Department, Assiut University, Assiut, Egypt.
Sayed MM; Radiation Oncology Department, South Egypt Cancer Institute, Assiut University, Assiut, Egypt.
Rayan A; Clinical Oncology Department, Assiut University, Assiut, Egypt.
Ali AM; Department of Medical Oncology, South Egypt Cancer Institute, Assiut University, Assiut, Egypt.
Hetta HF; Department of Medical Microbiology and Immunology, Faculty of Medicine, Assiut University, Assiut, Egypt.

Cancer Biomark ; 22(3): 587-595, 2018.

Article in En | MEDLINE | ID: mdl-29843224

Subject(s)

Antigens, CD/metabolism; Hepatitis A Virus Cellular Receptor 2/metabolism; Leukemia, Myeloid, Acute/diagnosis; Leukemia, Myeloid, Acute/metabolism; T-Lymphocytes, Regulatory/metabolism; Adult; Biomarkers, Tumor; Bone Marrow/pathology; Bone Marrow Cells/metabolism; Bone Marrow Cells/pathology; Case-Control Studies; Cytogenetic Analysis; Female; Flow Cytometry; Gene Expression; Humans; Immunophenotyping; Leukemia, Myeloid, Acute/etiology; Leukemia, Myeloid, Acute/mortality; Lymphocyte Count; Male; Prognosis; T-Lymphocytes, Regulatory/immunology

Key words

CD200; Regulatory T cells; TIM3; acute myeloid leukemia; normal cytogenetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Antigens, CD / T-Lymphocytes, Regulatory / Hepatitis A Virus Cellular Receptor 2 Type of study: Etiology_studies / Observational_studies / Prognostic_studies Limits: Adult / Female / Humans / Male Language: En Journal: Cancer Biomark Journal subject: BIOQUIMICA / NEOPLASIAS Year: 2018 Type: Article Affiliation country: Egypt

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