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Combining amplicon sequencing and metabolomics in cirrhotic patients highlights distinctive microbiota features involved in bacterial translocation, systemic inflammation and hepatic encephalopathy.
Iebba, Valerio; Guerrieri, Francesca; Di Gregorio, Vincenza; Levrero, Massimo; Gagliardi, Antonella; Santangelo, Floriana; Sobolev, Anatoly P; Circi, Simone; Giannelli, Valerio; Mannina, Luisa; Schippa, Serena; Merli, Manuela.
Affiliation
  • Iebba V; Istituto Pasteur Cenci Bolognetti Foundation, Public Health and Infectious Diseases Department, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.
  • Guerrieri F; Center for Life NanoScience@Sapienza, Istituto Italiano di Tecnologia, Rome, Italy.
  • Di Gregorio V; Gastroenterology, Department of Clinical Medicine, Sapienza University of Rome, Viale dell'Università 37, 00185, Rome, Italy.
  • Levrero M; Center for Life NanoScience@Sapienza, Istituto Italiano di Tecnologia, Rome, Italy.
  • Gagliardi A; INSERM, U1052, Cancer Research Center of Lyon (CRCL), Université de Lyon (UCBL1), Centre Léon Bérard, Lyon, France.
  • Santangelo F; Public Health and Infectious Diseases Department, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.
  • Sobolev AP; Public Health and Infectious Diseases Department, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.
  • Circi S; Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Rome, Italy.
  • Giannelli V; Magnetic Resonance Laboratory "Annalaura Segre", Institute of Chemical Methodologies, CNR, via Salaria km 29.300, 00015, Monterotondo, (RM), Italy.
  • Mannina L; Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Rome, Italy.
  • Schippa S; Gastroenterology, Department of Clinical Medicine, Sapienza University of Rome, Viale dell'Università 37, 00185, Rome, Italy.
  • Merli M; Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Rome, Italy.
Sci Rep ; 8(1): 8210, 2018 05 29.
Article in En | MEDLINE | ID: mdl-29844325
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Amplification / Hepatic Encephalopathy / Bacterial Translocation / Metabolomics / Microbiota / Inflammation / Liver Cirrhosis Limits: Humans Language: En Journal: Sci Rep Year: 2018 Type: Article Affiliation country: Italy
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Amplification / Hepatic Encephalopathy / Bacterial Translocation / Metabolomics / Microbiota / Inflammation / Liver Cirrhosis Limits: Humans Language: En Journal: Sci Rep Year: 2018 Type: Article Affiliation country: Italy