Beta-defensin derived cationic antimicrobial peptides with potent killing activity against gram negative and gram positive bacteria.

Yang, Ming; Zhang, Chunye; Zhang, Michael Z; Zhang, Shuping

Yang, Ming; Zhang, Chunye; Zhang, Michael Z; Zhang, Shuping.

Affiliation

Yang M; Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, MO, 65211, USA.
Zhang C; Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, MO, 65211, USA.
Zhang MZ; Department of Biomedical Science, College of Veterinary Medicine, University of Missouri, Columbia, MO, 65211, USA.
Zhang S; Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia, MO, 65211, USA.

BMC Microbiol ; 18(1): 54, 2018 06 05.

Article in En | MEDLINE | ID: mdl-29871599

Subject(s)

Antimicrobial Cationic Peptides/pharmacology; Gram-Negative Bacteria/drug effects; Gram-Positive Bacteria/drug effects; beta-Defensins/chemistry; Antimicrobial Cationic Peptides/chemical synthesis; Antimicrobial Cationic Peptides/chemistry; Circular Dichroism; Drug Resistance, Multiple, Bacterial; Methicillin-Resistant Staphylococcus aureus/drug effects; Microbial Sensitivity Tests; Models, Molecular; Protein Structure, Secondary; Pseudomonas aeruginosa/drug effects

Key words

Antimicrobial activity; Cationic antimicrobial peptides; Methicillin-resistant Staphylococcus pseudintermedius; Multidrug-resistant Pseudomonas aeruginosa; Peptide design; Salt resistance

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antimicrobial Cationic Peptides / Beta-Defensins / Gram-Negative Bacteria / Gram-Positive Bacteria Type of study: Prognostic_studies Language: En Journal: BMC Microbiol Journal subject: MICROBIOLOGIA Year: 2018 Type: Article Affiliation country: United States

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