Modulation of procollagen gene expression by retinoids. Inhibition of collagen production by retinoic acid accompanied by reduced type I procollagen messenger ribonucleic acid levels in human skin fibroblast cultures.

Oikarinen, H; Oikarinen, A I; Tan, E M; Abergel, R P; Meeker, C A; Chu, M L; Prockop, D J; Uitto, J

Oikarinen, H; Oikarinen, A I; Tan, E M; Abergel, R P; Meeker, C A; Chu, M L; Prockop, D J; Uitto, J.

J Clin Invest ; 75(5): 1545-53, 1985 May.

Article in En | MEDLINE | ID: mdl-2987306

Subject(s)

Collagen/antagonists & inhibitors; Gene Expression Regulation; Procollagen/antagonists & inhibitors; Skin/cytology; Tretinoin/pharmacology; Cells, Cultured; Collagen/biosynthesis; Endopeptidases/biosynthesis; Fibroblasts/metabolism; Humans; Keloid/metabolism; Mannose/metabolism; Microbial Collagenase/antagonists & inhibitors; Neprilysin; Procollagen/genetics; Procollagen/metabolism; RNA, Messenger/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin / Tretinoin / Gene Expression Regulation / Collagen / Procollagen Limits: Humans Language: En Journal: J Clin Invest Year: 1985 Type: Article

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