Multidrug efflux pumps: structure, function and regulation.

Du, Dijun; Wang-Kan, Xuan; Neuberger, Arthur; van Veen, Hendrik W; Pos, Klaas M; Piddock, Laura J V; Luisi, Ben F

Du, Dijun; Wang-Kan, Xuan; Neuberger, Arthur; van Veen, Hendrik W; Pos, Klaas M; Piddock, Laura J V; Luisi, Ben F.

Affiliation

Du D; Department of Biochemistry, University of Cambridge, Cambridge, UK.
Wang-Kan X; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK.
Neuberger A; Department of Biochemistry, University of Cambridge, Cambridge, UK.
van Veen HW; Department of Pharmacology, University of Cambridge, Cambridge, UK.
Pos KM; Department of Pharmacology, University of Cambridge, Cambridge, UK.
Piddock LJV; Institute of Biochemistry, Goethe Universität Frankfurt, Frankfurt, Germany.
Luisi BF; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK.

Nat Rev Microbiol ; 16(9): 523-539, 2018 09.

Article in En | MEDLINE | ID: mdl-30002505

Subject(s)

ATP-Binding Cassette Transporters/metabolism; Bacterial Proteins/metabolism; Drug Resistance, Bacterial; Drug Resistance, Multiple; ATP-Binding Cassette Transporters/genetics; Bacterial Proteins/genetics; Gram-Negative Bacteria/classification; Gram-Negative Bacteria/drug effects; Gram-Negative Bacterial Infections/drug therapy; Membrane Transport Proteins/genetics; Membrane Transport Proteins/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / Drug Resistance, Multiple / ATP-Binding Cassette Transporters / Drug Resistance, Bacterial Language: En Journal: Nat Rev Microbiol Journal subject: MICROBIOLOGIA Year: 2018 Type: Article Affiliation country: United kingdom

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