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EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation.
Zingg, Daniel; Debbache, Julien; Peña-Hernández, Rodrigo; Antunes, Ana T; Schaefer, Simon M; Cheng, Phil F; Zimmerli, Dario; Haeusel, Jessica; Calçada, Raquel R; Tuncer, Eylul; Zhang, Yudong; Bossart, Raphaël; Wong, Kwok-Kin; Basler, Konrad; Dummer, Reinhard; Santoro, Raffaella; Levesque, Mitchell P; Sommer, Lukas.
Affiliation
  • Zingg D; Stem Cell Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Debbache J; Stem Cell Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Peña-Hernández R; Department of Molecular Mechanisms of Disease, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland; Molecular Life Science PhD Program, Life Science Zurich Graduate School, 8057 Zurich, Switzerland.
  • Antunes AT; Stem Cell Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Schaefer SM; Stem Cell Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Cheng PF; Department of Dermatology, University Hospital Zurich, University of Zurich, Gloriastrasse 31, 8091 Zurich, Switzerland.
  • Zimmerli D; Institute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Haeusel J; Stem Cell Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Calçada RR; Stem Cell Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland; Cancer Biology PhD Program, Life Science Zurich Graduate School, 8057 Zurich, Switzerland.
  • Tuncer E; Stem Cell Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Zhang Y; Stem Cell Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland; Cancer Biology PhD Program, Life Science Zurich Graduate School, 8057 Zurich, Switzerland.
  • Bossart R; Stem Cell Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Wong KK; Division of Hematology & Medical Oncology, Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, 522 First Avenue, New York, NY 10016, USA.
  • Basler K; Institute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Dummer R; Department of Dermatology, University Hospital Zurich, University of Zurich, Gloriastrasse 31, 8091 Zurich, Switzerland.
  • Santoro R; Department of Molecular Mechanisms of Disease, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Levesque MP; Department of Dermatology, University Hospital Zurich, University of Zurich, Gloriastrasse 31, 8091 Zurich, Switzerland.
  • Sommer L; Stem Cell Biology, Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland. Electronic address: lukas.sommer@anatomy.uzh.ch.
Cancer Cell ; 34(1): 69-84.e14, 2018 07 09.
Article in En | MEDLINE | ID: mdl-30008323
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Cell Movement / Cilia / Cell Proliferation / Enhancer of Zeste Homolog 2 Protein / Melanocytes / Melanoma Limits: Animals / Female / Humans / Male Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2018 Type: Article Affiliation country: Switzerland
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Cell Movement / Cilia / Cell Proliferation / Enhancer of Zeste Homolog 2 Protein / Melanocytes / Melanoma Limits: Animals / Female / Humans / Male Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2018 Type: Article Affiliation country: Switzerland