Tight junction-associated protein GEF-H1 in the neighbours of dividing epithelial cells is essential for adaptation of cell-cell membrane during cytokinesis.

Hatte, Guillaume; Prigent, Claude; Tassan, Jean-Pierre

Hatte, Guillaume; Prigent, Claude; Tassan, Jean-Pierre.

Affiliation

Hatte G; Univ Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes) - UMR 6290, F35000 Rennes, France.
Prigent C; Univ Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes) - UMR 6290, F35000 Rennes, France.
Tassan JP; Univ Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes) - UMR 6290, F35000 Rennes, France. Electronic address: jean-pierre.tassan@univ-rennes1.fr.

Exp Cell Res ; 371(1): 72-82, 2018 10 01.

Article in En | MEDLINE | ID: mdl-30056063

Subject(s)

Cytokinesis/genetics; Epithelial Cells/metabolism; Gene Expression Regulation, Developmental; Mechanotransduction, Cellular; Rho Guanine Nucleotide Exchange Factors/genetics; Tight Junctions/metabolism; Xenopus Proteins/genetics; Actin Cytoskeleton/metabolism; Actin Cytoskeleton/ultrastructure; Adherens Junctions/metabolism; Adherens Junctions/ultrastructure; Amides/pharmacology; Animals; Cell Communication; Cell Membrane/metabolism; Cell Membrane/ultrastructure; Cell Shape; Embryo, Nonmammalian; Epithelial Cells/ultrastructure; Morpholinos/genetics; Morpholinos/metabolism; Protein Kinase Inhibitors/pharmacology; Pyridines/pharmacology; Rho Guanine Nucleotide Exchange Factors/antagonists & inhibitors; Rho Guanine Nucleotide Exchange Factors/deficiency; Tight Junctions/ultrastructure; Xenopus Proteins/antagonists & inhibitors; Xenopus Proteins/deficiency; Xenopus laevis; rho-Associated Kinases/antagonists & inhibitors; rho-Associated Kinases/genetics; rho-Associated Kinases/metabolism

Key words

Cytokinesis; Embryo; Epithelium; GEF-H1; Neighbours; Xenopus laevis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Developmental / Tight Junctions / Xenopus Proteins / Mechanotransduction, Cellular / Cytokinesis / Epithelial Cells / Rho Guanine Nucleotide Exchange Factors Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Exp Cell Res Year: 2018 Type: Article Affiliation country: France

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