Synthesis and Evaluation of Fuligocandin B Derivatives with Activity for Overcoming TRAIL Resistance.

Arai, Midori A; Masuda, Ayaka; Suganami, Akiko; Tamura, Yutaka; Ishibashi, Masami

Arai, Midori A; Masuda, Ayaka; Suganami, Akiko; Tamura, Yutaka; Ishibashi, Masami.

Affiliation

Arai MA; Graduate School of Pharmaceutical Sciences, Chiba University.
Masuda A; Graduate School of Pharmaceutical Sciences, Chiba University.
Suganami A; Graduate School of Medicine, Chiba University.
Tamura Y; Graduate School of Medicine, Chiba University.
Ishibashi M; Graduate School of Pharmaceutical Sciences, Chiba University.

Chem Pharm Bull (Tokyo) ; 66(8): 810-817, 2018.

Article in En | MEDLINE | ID: mdl-30068801

Subject(s)

Antineoplastic Agents/chemical synthesis; Drug Resistance, Neoplasm/drug effects; Proline/analogs & derivatives; TNF-Related Apoptosis-Inducing Ligand/metabolism; Antineoplastic Agents/pharmacology; Apoptosis/drug effects; Cell Line, Tumor; Cell Survival/drug effects; Drug Design; Humans; Molecular Docking Simulation; Proline/chemical synthesis; Proline/pharmacology; Structure-Activity Relationship

Key words

cancer; cytotoxicity; inhibitor; natural product; tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proline / Drug Resistance, Neoplasm / TNF-Related Apoptosis-Inducing Ligand / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Chem Pharm Bull (Tokyo) Year: 2018 Type: Article

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