Giant multivesicular bodies in the rat hippocampal pyramidal cells after chronic alcohol consumption.
Neurosci Lett
; 64(3): 345-9, 1986 Mar 14.
Article
in En
| MEDLINE
| ID: mdl-3008045
ABSTRACT
Multivesicular bodies (MVBs) with diameters up to 4.5 microns were observed in the hippocampal pyramidal cells of rats submitted to chronic alcohol consumption. A significant increase in the volumetric density (Vv) of these organelles was found in CA1 pyramidal cells. Transitional forms of MVBs towards lysosomes were seen. A failure in MVB's enzymatic hydrolytic mechanisms, due to the prolonged alcohol aggression, could underlie its formation.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Inclusion Bodies
/
Alcoholism
/
Hippocampus
/
Neurons
Limits:
Animals
Language:
En
Journal:
Neurosci Lett
Year:
1986
Type:
Article