Kinetic analysis of the influenza A virus HA/NA balance reveals contribution of NA to virus-receptor binding and NA-dependent rolling on receptor-containing surfaces.

Guo, Hongbo; Rabouw, Huib; Slomp, Anne; Dai, Meiling; van der Vegt, Floor; van Lent, Jan W M; McBride, Ryan; Paulson, James C; de Groot, Raoul J; van Kuppeveld, Frank J M; de Vries, Erik; de Haan, Cornelis A M

Guo, Hongbo; Rabouw, Huib; Slomp, Anne; Dai, Meiling; van der Vegt, Floor; van Lent, Jan W M; McBride, Ryan; Paulson, James C; de Groot, Raoul J; van Kuppeveld, Frank J M; de Vries, Erik; de Haan, Cornelis A M.

Affiliation

Guo H; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Rabouw H; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Slomp A; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Dai M; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
van der Vegt F; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
van Lent JWM; Laboratory of Virology, Wageningen University and Research, Droevendaalsesteeg 1, PB Wageningen, the Netherlands.
McBride R; Departments of Cell and Molecular Biology, Chemical Physiology, and Immunology and Microbial Science, Scripps Research Institute, La Jolla, California, United States of America.
Paulson JC; Departments of Cell and Molecular Biology, Chemical Physiology, and Immunology and Microbial Science, Scripps Research Institute, La Jolla, California, United States of America.
de Groot RJ; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
van Kuppeveld FJM; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
de Vries E; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
de Haan CAM; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.

PLoS Pathog ; 14(8): e1007233, 2018 08.

Article in En | MEDLINE | ID: mdl-30102740

Subject(s)

Hemagglutinin Glycoproteins, Influenza Virus/metabolism; Influenza A virus/physiology; Neuraminidase/metabolism; Receptors, Virus/metabolism; Virus Attachment; Virus Internalization; Animals; CHO Cells; Cricetinae; Cricetulus; HEK293 Cells; Hemagglutinin Glycoproteins, Influenza Virus/analysis; Hemagglutinin Glycoproteins, Influenza Virus/genetics; Humans; Influenza A virus/metabolism; Kinetics; Neuraminidase/analysis; Neuraminidase/genetics; Protein Binding; Receptors, Virus/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Influenza A virus / Receptors, Virus / Hemagglutinin Glycoproteins, Influenza Virus / Virus Attachment / Virus Internalization / Neuraminidase Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS Pathog Year: 2018 Type: Article Affiliation country: Netherlands

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