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Impact of ring size and drug loading on the pharmacokinetics of a combination dapivirine-darunavir vaginal ring in cynomolgus macaques.
Murphy, Diarmaid J; Desjardins, Delphine; Boyd, Peter; Dereuddre-Bosquet, Nathalie; Stimmer, Lev; Caldwell, Anna; Le Grand, Roger; Kelly, Charles; van Roey, Jens; Malcolm, R Karl.
Affiliation
  • Murphy DJ; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK. Electronic address: d.j.murphy@qub.ac.uk.
  • Desjardins D; Université Paris Sud, INSERM, CEA, DRF-Immunology of Viral Infections and Autoimmune Diseases Department (IMVA), U1184, IDMIT Infrastructure, Fontenay-aux-Roses, France. Electronic address: delphine.desjardins@cea.fr.
  • Boyd P; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK. Electronic address: p.boyd@qub.ac.uk.
  • Dereuddre-Bosquet N; Université Paris Sud, INSERM, CEA, DRF-Immunology of Viral Infections and Autoimmune Diseases Department (IMVA), U1184, IDMIT Infrastructure, Fontenay-aux-Roses, France. Electronic address: nathalie.bosquet@cea.fr.
  • Stimmer L; Molecular Imaging Research Center, CEA-INSERM US27/U1169, 18 route du Panorama, 92265 Fontenay-aux-Roses, France. Electronic address: lev.stimmer@cea.fr.
  • Caldwell A; Mass Spectrometry Facility, King's College London, London SE1 9NH, UK. Electronic address: anna.caldwell@kcl.ac.uk.
  • Le Grand R; Université Paris Sud, INSERM, CEA, DRF-Immunology of Viral Infections and Autoimmune Diseases Department (IMVA), U1184, IDMIT Infrastructure, Fontenay-aux-Roses, France. Electronic address: roger.le-grand@cea.fr.
  • Kelly C; Dental Institute, Guy's Hospital, King's College London, London SE1 9RT, UK. Electronic address: charles.kelly@kcl.ac.uk.
  • van Roey J; Janssen GPH, Turnhoutseweg 30, 2340 Beerse, Belgium. Electronic address: JVROEY@its.jnj.com.
  • Malcolm RK; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK. Electronic address: k.malcolm@qub.ac.uk.
Int J Pharm ; 550(1-2): 300-308, 2018 Oct 25.
Article in En | MEDLINE | ID: mdl-30153490
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Contraceptive Devices, Female / Anti-HIV Agents / Darunavir Limits: Animals Language: En Journal: Int J Pharm Year: 2018 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Contraceptive Devices, Female / Anti-HIV Agents / Darunavir Limits: Animals Language: En Journal: Int J Pharm Year: 2018 Type: Article