Chitosan nanoparticles as a promising approach for pulmonary delivery of bedaquiline.

Rawal, Tejal; Patel, Snehal; Butani, Shital

Rawal, Tejal; Patel, Snehal; Butani, Shital.

Affiliation

Rawal T; Institute of Pharmacy, Nirma University, Ahmedabad 382481, India.
Patel S; Institute of Pharmacy, Nirma University, Ahmedabad 382481, India.
Butani S; Institute of Pharmacy, Nirma University, Ahmedabad 382481, India. Electronic address: shital.butani@nirmauni.ac.in.

Eur J Pharm Sci ; 124: 273-287, 2018 Nov 01.

Article in En | MEDLINE | ID: mdl-30176365

Subject(s)

Antitubercular Agents/administration & dosage; Chitosan/administration & dosage; Diarylquinolines/administration & dosage; Drug Carriers/administration & dosage; Nanoparticles/administration & dosage; Administration, Inhalation; Animals; Antitubercular Agents/chemistry; Antitubercular Agents/pharmacokinetics; Cell Line; Chitosan/chemistry; Diarylquinolines/chemistry; Diarylquinolines/pharmacokinetics; Drug Carriers/chemistry; Drug Liberation; Lung/drug effects; Lung/metabolism; Male; Mice; Nanoparticles/chemistry; Rats, Wistar

Key words

Bedaquiline; Cascade impactor; Chitosan; Freeze drying; Nanoparticles; Pharmacokinetics; Pulmonary

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Carriers / Chitosan / Nanoparticles / Diarylquinolines / Antitubercular Agents Limits: Animals Language: En Journal: Eur J Pharm Sci Journal subject: FARMACIA / FARMACOLOGIA / QUIMICA Year: 2018 Type: Article Affiliation country: India

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