Enterotoxigenic Escherichia coli heat labile enterotoxin inhibits intestinal ascorbic acid uptake via a cAMP-dependent NF-&#954;B-mediated pathway.

Subramenium, Ganapathy A; Sabui, Subrata; Marchant, Jonathan S; Said, Hamid M; Subramanian, Veedamali S

Enterotoxigenic Escherichia coli heat labile enterotoxin inhibits intestinal ascorbic acid uptake via a cAMP-dependent NF-κB-mediated pathway.

Subramenium, Ganapathy A; Sabui, Subrata; Marchant, Jonathan S; Said, Hamid M; Subramanian, Veedamali S.

Affiliation

Subramenium GA; Department of Medicine, University of California , Irvine, California.
Sabui S; Department of Veterans Affairs Medical Center , Long Beach, California.
Marchant JS; Department of Medicine, University of California , Irvine, California.
Said HM; Department of Physiology and Biophysics, University of California , Irvine, California.
Subramanian VS; Department of Veterans Affairs Medical Center , Long Beach, California.

Am J Physiol Gastrointest Liver Physiol ; 316(1): G55-G63, 2019 01 01.

Article in En | MEDLINE | ID: mdl-30285481

Subject(s)

Ascorbic Acid/pharmacology; Enterotoxigenic Escherichia coli/chemistry; Animals; Biological Transport/drug effects; Caco-2 Cells; Enterotoxins/metabolism; Epithelial Cells/drug effects; Epithelial Cells/metabolism; Escherichia coli Infections/metabolism; Humans; Intestinal Mucosa/drug effects; Intestinal Mucosa/metabolism; Intestines/drug effects; NF-kappa B/metabolism; Sodium-Coupled Vitamin C Transporters/drug effects; Sodium-Coupled Vitamin C Transporters/metabolism; Vitamins/metabolism

Key words

SVCT1; SVCT2; vitamin C

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ascorbic Acid / Enterotoxigenic Escherichia coli Limits: Animals / Humans Language: En Journal: Am J Physiol Gastrointest Liver Physiol Journal subject: FISIOLOGIA / GASTROENTEROLOGIA Year: 2019 Type: Article

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