Fluorescent Biosensor for Detection of the R248Q Aggregation-Prone Mutant of p53.

Pellerano, Morgan; Naud-Martin, Delphine; Mahuteau-Betzer, Florence; Morille, Marie; Morris, May C

Pellerano, Morgan; Naud-Martin, Delphine; Mahuteau-Betzer, Florence; Morille, Marie; Morris, May C.

Affiliation

Pellerano M; Institut des Biomolécules Max Mousseron-IBMM-UMR 5247, Université de Montpellier, Faculté de Pharmacie, 15, Av. Charles Flahault, 34093, Montpellier, France.
Naud-Martin D; Institut Curie, PSL Research University, CNRS, INSERM, UMR9187-U1196, 91405, Orsay, France.
Mahuteau-Betzer F; Institut Curie, PSL Research University, CNRS, INSERM, UMR9187-U1196, 91405, Orsay, France.
Morille M; Institut Charles Gerhardt-UMR 5253 CNRS-UM-ENSCM, Université de Montpellier, Faculté de Pharmacie, 15, Av. Charles Flahault, 34093, Montpellier, France.
Morris MC; Institut des Biomolécules Max Mousseron-IBMM-UMR 5247, Université de Montpellier, Faculté de Pharmacie, 15, Av. Charles Flahault, 34093, Montpellier, France.

Chembiochem ; 20(4): 605-613, 2019 02 15.

Article in En | MEDLINE | ID: mdl-30548750

Subject(s)

Biosensing Techniques/methods; Fluorescein-5-isothiocyanate/chemistry; Tumor Suppressor Protein p53/genetics; Amino Acid Sequence; Cell Line, Tumor; Humans; Microscopy, Fluorescence; Mutation, Missense; Peptides/chemistry; Peptides/metabolism

Key words

aggregation; biosensors; cancer; fluorescence; peptides

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biosensing Techniques / Tumor Suppressor Protein p53 / Fluorescein-5-isothiocyanate Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Chembiochem Journal subject: BIOQUIMICA Year: 2019 Type: Article Affiliation country: France

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