Design, Synthesis, and Biological Evaluation of Itaconic Acid Derivatives as Potential Anti-Influenza Agents.

Sethy, Bidyadhar; Hsieh, Chung-Fan; Lin, Ta-Jen; Hu, Po-Yuan; Chen, Yu-Li; Lin, Chia-Yi; Tseng, Sung-Nain; Horng, Jim-Tong; Hsieh, Pei-Wen

Sethy, Bidyadhar; Hsieh, Chung-Fan; Lin, Ta-Jen; Hu, Po-Yuan; Chen, Yu-Li; Lin, Chia-Yi; Tseng, Sung-Nain; Horng, Jim-Tong; Hsieh, Pei-Wen.

Affiliation

Horng JT; Molecular Infectious Disease Research Center, Chang Gung Memorial Hospital, College of Medicine , Chang Gung University , Linkou 333 , Taiwan.
Hsieh PW; Research Center for Chinese Herbal Medicine , Chang Gung University of Science and Technology , Taoyuan 33303 , Taiwan.

J Med Chem ; 62(5): 2390-2403, 2019 03 14.

Article in En | MEDLINE | ID: mdl-30753063

Subject(s)

Antiviral Agents/chemistry; Antiviral Agents/pharmacology; Drug Design; Influenza A virus/drug effects; Succinates/chemistry; Succinates/pharmacology; Animals; Antiviral Agents/chemical synthesis; Dogs; Influenza A virus/classification; Influenza A virus/physiology; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Species Specificity; Structure-Activity Relationship; Succinates/chemical synthesis; Virus Replication/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Influenza A virus / Succinates / Drug Design Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2019 Type: Article

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