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Loss of BOP1 confers resistance to BRAF kinase inhibitors in melanoma by activating MAP kinase pathway.
Gupta, Romi; Bugide, Suresh; Wang, Biao; Green, Michael R; Johnson, Douglas B; Wajapeyee, Narendra.
Affiliation
  • Gupta R; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510.
  • Bugide S; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510.
  • Wang B; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510.
  • Green MR; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605; narendra.wajapeyee@yale.edu michael.green@umassmed.edu.
  • Johnson DB; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37240.
  • Wajapeyee N; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605; narendra.wajapeyee@yale.edu michael.green@umassmed.edu.
Proc Natl Acad Sci U S A ; 116(10): 4583-4591, 2019 03 05.
Article in En | MEDLINE | ID: mdl-30782837
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA-Binding Proteins / Drug Resistance, Neoplasm / Proto-Oncogene Proteins B-raf / Protein Kinase Inhibitors / Melanoma Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Proc Natl Acad Sci U S A Year: 2019 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA-Binding Proteins / Drug Resistance, Neoplasm / Proto-Oncogene Proteins B-raf / Protein Kinase Inhibitors / Melanoma Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Proc Natl Acad Sci U S A Year: 2019 Type: Article