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Phase 1 Open-Label, Multicenter Study of First-in-Class RORγ Agonist LYC-55716 (Cintirorgon): Safety, Tolerability, and Preliminary Evidence of Antitumor Activity.
Mahalingam, Devalingam; Wang, Judy S; Hamilton, Erika P; Sarantopoulos, John; Nemunaitis, John; Weems, Garry; Carter, Laura; Hu, Xiao; Schreeder, Marshall; Wilkins, H Jeffrey.
Affiliation
  • Mahalingam D; Department of Medicine, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois.
  • Wang JS; Drug Development Unit, Sarah Cannon Research Institute at Florida Cancer Specialists, Sarasota, Florida.
  • Hamilton EP; Breast Cancer and Gynecologic Cancer Research Program, Sarah Cannon Research Institute, Nashville, Tennessee.
  • Sarantopoulos J; Division of Hematology-Oncology, University of Texas Health Science Center at San Antonio, San Antonio, Texas.
  • Nemunaitis J; Executive Medical Director, Mary Crowley Cancer Research, Dallas, Texas.
  • Weems G; Clinical Development, Lycera Corp., Plymouth Meeting, Pennsylvania. weems@lycera.com.
  • Carter L; Biology, Lycera Corp., Ann Arbor, Michigan.
  • Hu X; Biology, Lycera Corp., Ann Arbor, Michigan.
  • Schreeder M; Medical Oncology, Clearview Cancer Institute, Huntsville, Alabama.
  • Wilkins HJ; Clinical Development, Lycera Corp., Plymouth Meeting, Pennsylvania.
Clin Cancer Res ; 25(12): 3508-3516, 2019 06 15.
Article in En | MEDLINE | ID: mdl-30819679
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propionates / Receptors, Retinoic Acid / Benzoxazines / Neoplasm Recurrence, Local / Neoplasms / Antineoplastic Agents Type of study: Clinical_trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2019 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propionates / Receptors, Retinoic Acid / Benzoxazines / Neoplasm Recurrence, Local / Neoplasms / Antineoplastic Agents Type of study: Clinical_trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2019 Type: Article