Quantitative and Specific Detection of Exosomal miRNAs for Accurate Diagnosis of Breast Cancer Using a Surface-Enhanced Raman Scattering Sensor Based on Plasmonic Head-Flocked Gold Nanopillars.

Lee, Jong Uk; Kim, Woo Hyun; Lee, Hye Sun; Park, Kyong Hwa; Sim, Sang Jun

Lee, Jong Uk; Kim, Woo Hyun; Lee, Hye Sun; Park, Kyong Hwa; Sim, Sang Jun.

Affiliation

Lee JU; Department of Chemical and Biological Engineering, Korea University, Seoul, 02841, Korea.
Kim WH; Department of Chemical and Biological Engineering, Korea University, Seoul, 02841, Korea.
Lee HS; Division of Oncology/Hematology, Department of Internal Medicine, Korea University College of Medicine, Seoul, 02841, Korea.
Park KH; Division of Oncology/Hematology, Department of Internal Medicine, Korea University College of Medicine, Seoul, 02841, Korea.
Sim SJ; Department of Chemical and Biological Engineering, Korea University, Seoul, 02841, Korea.

Small ; 15(17): e1804968, 2019 04.

Article in En | MEDLINE | ID: mdl-30828996

Subject(s)

Breast Neoplasms/blood; Breast Neoplasms/diagnosis; Exosomes/chemistry; Gold/chemistry; Metal Nanoparticles/chemistry; MicroRNAs/analysis; Biomarkers, Tumor/blood; Biosensing Techniques; Calibration; Cell Line, Tumor; Female; Humans; Limit of Detection; Oligonucleotides/chemistry; Prognosis; Scattering, Radiation; Serum/chemistry; Spectrum Analysis, Raman; Surface Properties

Key words

cancer diagnosis; exosome; microRNA; plasmonic head-flocked gold nanopillar; surface-enhanced Raman scattering (SERS)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / MicroRNAs / Metal Nanoparticles / Exosomes / Gold Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Female / Humans Language: En Journal: Small Journal subject: ENGENHARIA BIOMEDICA Year: 2019 Type: Article

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