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Impact of depth filtration on disulfide bond reduction during downstream processing of monoclonal antibodies from CHO cell cultures.
O'Mara, Brian; Gao, Zhong-Hua; Kuruganti, Manju; Mallett, Robert; Nayar, Gautam; Smith, Laura; Meyer, Jeffrey D; Therriault, Jon; Miller, Cameron; Cisney, John; Fann, John.
Affiliation
  • O'Mara B; BioProcess Development, Bristol-Myers Squibb Co., Seattle, Washington.
  • Gao ZH; BioProcess Development, Bristol-Myers Squibb Co., Seattle, Washington.
  • Kuruganti M; BioProcess Development, Bristol-Myers Squibb Co., Seattle, Washington.
  • Mallett R; BioProcess Development, Bristol-Myers Squibb Co., Seattle, Washington.
  • Nayar G; BioProcess Development, Bristol-Myers Squibb Co., Seattle, Washington.
  • Smith L; BioProcess Development, Bristol-Myers Squibb Co., Seattle, Washington.
  • Meyer JD; BioProcess Development, Bristol-Myers Squibb Co., Seattle, Washington.
  • Therriault J; BioProcess Development, Bristol-Myers Squibb Co., Seattle, Washington.
  • Miller C; BioProcess Development, Bristol-Myers Squibb Co., Seattle, Washington.
  • Cisney J; BioProcess Development, Bristol-Myers Squibb Co., Seattle, Washington.
  • Fann J; BioProcess Development, Bristol-Myers Squibb Co., Seattle, Washington.
Biotechnol Bioeng ; 116(7): 1669-1683, 2019 07.
Article in En | MEDLINE | ID: mdl-30883673
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Disulfides / Antibodies, Monoclonal Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Biotechnol Bioeng Year: 2019 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Disulfides / Antibodies, Monoclonal Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Biotechnol Bioeng Year: 2019 Type: Article