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A CD40L-targeting protein reduces autoantibodies and improves disease activity in patients with autoimmunity.
Karnell, Jodi L; Albulescu, Marius; Drabic, Stacey; Wang, Liangwei; Moate, Rachel; Baca, Manuel; Oganesyan, Vaheh; Gunsior, Michele; Thisted, Thomas; Yan, Li; Li, Jing; Xiong, Ximing; Eck, Steven C; de Los Reyes, Melissa; Yusuf, Isharat; Streicher, Katie; Müller-Ladner, Ulf; Howe, David; Ettinger, Rachel; Herbst, Ronald; Drappa, Jörn.
Affiliation
  • Karnell JL; Viela Bio, Gaithersburg, MD 20878, USA.
  • Albulescu M; AstraZeneca, Cambridge CB4 OWG, UK.
  • Drabic S; MedImmune, Gaithersburg, MD 20878, USA.
  • Wang L; Viela Bio, Gaithersburg, MD 20878, USA.
  • Moate R; MedImmune, Granta Park, Cambridge CB21 6GH, UK.
  • Baca M; MedImmune, Gaithersburg, MD 20878, USA.
  • Oganesyan V; MedImmune, Gaithersburg, MD 20878, USA.
  • Gunsior M; Viela Bio, Gaithersburg, MD 20878, USA.
  • Thisted T; MedImmune, Gaithersburg, MD 20878, USA.
  • Yan L; Viela Bio, Gaithersburg, MD 20878, USA.
  • Li J; MedImmune, San Francisco, CA 94080, USA.
  • Xiong X; MedImmune, Gaithersburg, MD 20878, USA.
  • Eck SC; MedImmune, Gaithersburg, MD 20878, USA.
  • de Los Reyes M; MedImmune, Gaithersburg, MD 20878, USA.
  • Yusuf I; MedImmune, Gaithersburg, MD 20878, USA.
  • Streicher K; MedImmune, Gaithersburg, MD 20878, USA.
  • Müller-Ladner U; Department of Rheumatology and Clinical Immunology, Campus Kerchoff, Justus-Liebig University Giessen, 61231 Bad Nauheim, Germany.
  • Howe D; MedImmune, Granta Park, Cambridge CB21 6GH, UK.
  • Ettinger R; Viela Bio, Gaithersburg, MD 20878, USA.
  • Herbst R; MedImmune, Gaithersburg, MD 20878, USA. herbstro@medimmune.com drappaj@vielabio.com.
  • Drappa J; Viela Bio, Gaithersburg, MD 20878, USA. herbstro@medimmune.com drappaj@vielabio.com.
Sci Transl Med ; 11(489)2019 04 24.
Article in En | MEDLINE | ID: mdl-31019027

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoantibodies / Autoimmunity / Platelet Aggregation / CD40 Ligand / Cell Proliferation Limits: Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2019 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoantibodies / Autoimmunity / Platelet Aggregation / CD40 Ligand / Cell Proliferation Limits: Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2019 Type: Article Affiliation country: United States