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SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis.
Huang, Linzhang; Chambliss, Ken L; Gao, Xiaofei; Yuhanna, Ivan S; Behling-Kelly, Erica; Bergaya, Sonia; Ahmed, Mohamed; Michaely, Peter; Luby-Phelps, Kate; Darehshouri, Anza; Xu, Lin; Fisher, Edward A; Ge, Woo-Ping; Mineo, Chieko; Shaul, Philip W.
Affiliation
  • Huang L; Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Chambliss KL; Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Gao X; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Yuhanna IS; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Behling-Kelly E; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Bergaya S; Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Ahmed M; Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Michaely P; Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Luby-Phelps K; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
  • Darehshouri A; Department of Medicine, New York University School of Medicine, New York, NY, USA.
  • Xu L; Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, NY, USA.
  • Fisher EA; Marc and Ruti Bell Program in Vascular Biology, New York University School of Medicine, New York, NY, USA.
  • Ge WP; Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Mineo C; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Shaul PW; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Nature ; 569(7757): 565-569, 2019 05.
Article in En | MEDLINE | ID: mdl-31019307

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arteries / GTPase-Activating Proteins / Endothelial Cells / Atherosclerosis / Scavenger Receptors, Class B / Transcytosis / Cholesterol, LDL Limits: Animals / Female / Humans / Male Language: En Journal: Nature Year: 2019 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arteries / GTPase-Activating Proteins / Endothelial Cells / Atherosclerosis / Scavenger Receptors, Class B / Transcytosis / Cholesterol, LDL Limits: Animals / Female / Humans / Male Language: En Journal: Nature Year: 2019 Type: Article Affiliation country: United States