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PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy.
Tu, Xinyi; Qin, Bo; Zhang, Yong; Zhang, Cheng; Kahila, Mohamed; Nowsheen, Somaira; Yin, Ping; Yuan, Jian; Pei, Huadong; Li, Hu; Yu, Jia; Song, Zhiwang; Zhou, Qin; Zhao, Fei; Liu, Jiaqi; Zhang, Chao; Dong, Haidong; Mutter, Robert W; Lou, Zhenkun.
Affiliation
  • Tu X; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
  • Qin B; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
  • Zhang Y; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
  • Zhang C; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.
  • Kahila M; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.
  • Nowsheen S; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
  • Yin P; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
  • Yuan J; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
  • Pei H; Department of Biochemistry and Molecular Medicine, George Washington University School of Medicine and Health Science, 2300 Eye Street, NW, Washington, DC 20037, USA.
  • Li H; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.
  • Yu J; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.
  • Song Z; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
  • Zhou Q; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
  • Zhao F; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
  • Liu J; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
  • Zhang C; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
  • Dong H; Department of Urology, Mayo Clinic, Rochester, MN 55905, USA. Electronic address: dong.haidong@mayo.edu.
  • Mutter RW; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA. Electronic address: mutter.robert@mayo.edu.
  • Lou Z; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA. Electronic address: lou.zhenkun@mayo.edu.
Mol Cell ; 74(6): 1215-1226.e4, 2019 06 20.
Article in En | MEDLINE | ID: mdl-31053471
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Neoplasm / Gene Expression Regulation, Neoplastic / DNA Repair / B7-H1 Antigen / Programmed Cell Death 1 Receptor / Exosome Multienzyme Ribonuclease Complex Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2019 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Neoplasm / Gene Expression Regulation, Neoplastic / DNA Repair / B7-H1 Antigen / Programmed Cell Death 1 Receptor / Exosome Multienzyme Ribonuclease Complex Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2019 Type: Article Affiliation country: United States